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      Pharmacology News
      December 3, 2020

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      Researchers have found new forms of tau protein that become abnormal in the very early stages of Alzheimer's disease before ...

      Environmental Exposures Affect Therapeutic Drugs

      Humans are exposed to various environmental or dietary molecules that can attenuate or even increase the effect of therapeutic drugs. Studies on the industrial chemical bisphenol A and the ...

      Drug Reverses Age-Related Mental Decline Within Days, Mouse Study Shows

      Just a few doses of an experimental drug can reverse age-related declines in memory and mental flexibility in mice, according to a new study. The drug, called ISRIB, has already been shown in ...

      'Anti-Antibiotic' Allows for Use of Antibiotics Without Driving Resistance

      An inexpensive, FDA-approved drug -- cholestyramine -- taken in conjunction with an antibiotic prevents the antibiotic from driving antimicrobial resistance, according to new ...
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      updated 8:59pm EST

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      No Nanoparticle Risks to Humans Found in Field Tests of Spray Sunscreens

      People can continue using mineral-based aerosol sunscreens without fear of exposure to dangerous levels of nanoparticles or other respirable particulates, according to new ...

      Statins Can Save Lives; Are They Being Used?

      People who have coronary artery disease, stroke or peripheral artery disease often are prescribed a statin, a cholesterol-lowering drug that reduces the risk of heart attack or ...

      Researchers Develop Customized Targeting of Bacteria Using Lysins

      Researchers have developed a method to produce engineered lysins that can be used to selectively kill bacteria of interest while leaving others unharmed. The discovery presents a promising ...

      Plants on Aspirin

      For centuries humans were using willow barks to treat a headache or an inflamed tooth. Later, the active ingredient, the plant hormone salicylic acid, was used to develop painkillers like Aspirin. ...

      Warning Signs Over Effectiveness of HIV 'Wonder Drug' in Sub-Saharan Africa

      Dolutegravir, the current first-line treatment for HIV, may not be as effective as hoped in sub-Saharan Africa, suggests new research published on World AIDS Day. The study finds that this so-called ...

      AI Predicts Which Drug Combinations Kill Cancer Cells

      A machine learning model can help us treat cancer more ...

      New Device Offers Faster Way to Detect Antibiotic-Resistant Bacteria

      A new device for faster testing of antibiotic-resistant bacteria has been ...

      Microfluidic System With Cell-Separating Powers May Unravel How Novel Pathogens Attack

      To develop effective therapeutics against pathogens, scientists need to first uncover how they attack host cells. An efficient way to conduct these investigations on an extensive scale is through ...

      Combination Therapy Might Improve Outcomes in Treatment-Resistant Liver Cancer

      A combination cancer therapy that is effective against treatment-resistant hepatocellular carcinoma (HCC) by inhibiting tumor growth and increasing survival has been identified. The dual therapy -- ...

      New Method Identifies Adaptive Mutations in Complex Evolving Populations

      A scientist has developed a method to study how HIV mutates to escape the immune system in multiple individuals, which could inform HIV vaccine ...

      Researchers Unlock the Door to Tumor Microenvironment for CAR T Cells

      Combining chimeric antigen receptor (CAR) T cell therapy with a PAK4 inhibitor drug allowed the engineered cells to punch their way through and attack solid tumors, leading to significantly enhanced ...

      Scientists Design Model to Predict Cellular Drug Targets Against COVID-19

      A computational model of a human lung cell has been used to understand how SARS-CoV-2 draws on human host cell metabolism to reproduce. This study helps understand how the virus uses the host to ...

      New Mechanism of Pain Control Revealed

      Researchers have identified a unique population of astrocytes in the dorsal horn of the spinal cord of mice that produces pain hypersensitivity when activated by neurons carrying signals down from ...

      New Plant-Based Gel to Fast-Track 'Mini-Organs' Growth, Improve Cancer Treatment

      Researchers have created the world's first bioactive plant-based nanocellulose hydrogel to support organoid growth for biomedical applications. This includes cancer development and ...

      Simple New Testing Method Aims to Improve Time-Release Drugs

      Engineers filled a glass tube bent like a tuning fork, kept vibrating by a circuit at its resonance frequency, with simulated stomach and intestine contents and passed an over-the-counter ...

      Commonly Used Antibiotic Shows Promise for Combating Zika Infections

      Researchers used a variety of advanced drug screening techniques to test out more than 10,000 compounds in search of a cure. To their surprise, they found that the widely used antibiotic methacycline ...

      Sestrin Makes Fruit Flies Live Longer

      Researchers identify positive effector behind reduced food ...

      Channeling the Immune System for Head and Neck Cancer

      Researchers have discovered new clues into why some people with head and neck cancer respond to immunotherapy, while others ...

      How the Brain 'Re-Wires' After Disease

      Researchers are studying how the brain re-wires itself in neurological disease. The team is building treatments for today's more common global conditions like Motor Neuron Disease (MND/ALS) and ...

      World's First: Drug Guides Stem Cells to Desired Location, Improving Their Ability to Heal

      Scientists have created a drug that can lure stem cells to damaged tissue and improve treatment efficacy -- a scientific first and major advance for the field of regenerative ...

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